Published online 4/8/2022
Published PubMed Oct 2022
Benefits of PVP-I Oro-Nasal Spray in Brief
Benefits of 0.6% PVP-I
- Effective virucidal agent against all coronaviruses, including SARS- COV-2.
- Effective in case of both pre and post exposure.
- Effective for healthy individual (for protection) as well as COVID-19 patient also ( for reduction of viral load and SARS-CoV-2 transmissibility for close contacts/ family members).
- Almost no side effect (mucosal irritation, thyroid dysfunction, teeth staining,).
- This minimum concentration of PVP-I (0.6%) has least possibility of doing any harm to human body (nasal or oral mucosa). More concentration is being used on eye, ear, mucosa of oral cavity, oropharynx since before.
- No chance of resistance
- Reduces disease burden by minimizing sign- symptoms, like-nasal congestion, sore throat.
Benefits of Oro-Nasal Spray
- Single container, double function (PVP-I Oral/Throat spray as well as Nasal spray)
- Easy to carry (in pocket, handbag)
- Easy to use
- No need to have a basin or a facility to gargle or spit
- Minimum amount of PVP-I solution is needed (20 ml solution can be used for 20- 30 days for regular user.)
- Cheap (to refill)
- Minimum Iodine exposure.
- Container can be reusable and refillable.
Recommendations
PVP-I Oro Nasal Spray should be used by doctors or other health care workers (HCW), COVID-19 patients as well as common people.
For Doctors or Other Health Care Workers (HCW).
- Prior to visit any patient in any facility irrespective of COVID status
- Prior to examining the oral cavity, throat or nose of any patient
- Prior to any Surgery, specially surgery of Nose, mouth, throat, ear, skull base
- Prior to attend COVID-19 patient in a COVID-19 dedicated unit / hospital
- Following exposure to confirmed or suspected COVID patient (intentional/accidental)
For Common People
- Prior to attend public gathering or working outside home, where there is chance of known or unknown COVID-19 patient/ SARS-CoV-2 exposure.
- Before leaving and after returning home and in between 1 or 2 time (after tea/lunch/dinner break).
- For COVID-19 patientsAs it has the potentiality to reduce the viral load, it will definitely reduce the viral transmission from patient to healthy person. Again, it may have positive role on treatment, in mortality and morbidity index. To prove this further studies are recommended.
- How to use: 2–3 puff in each nostril and 1–3 puff in throat (oral cavity and oropharynx) in 3–4 h interval.
- How long? Though it is proved and established that long term (1–2 months) application of this minimum amount of PVP-I is quite safe SPS:refid::bib2|bib3|bib4[2,3,4]. But, I recommend after continuous use of 1–2 week 1 day interval (weekly holiday) should be given.
Conclusion
PPE, mask, hand sanitization or vaccines nothing proved 100% effective for COVID-19 prevention still now. PVP-I oro-nasal spray is an easy tool or way for COVID-19 prevention and reduction of SARS-CoV-2 transmissibility. I recommend here, this oro-nasal spray should be used as an adjunct to PPE, mask or vaccine. Any person, policy maker, local or central government could adopt this safe, cheap, easily available and effective PVP-I Oro-Nasal spray as an additional shield of their COVID-19 protection and thus minimize the COVID burden.