Category: Covid “Pinned to Top” Posts

Using Hydrogen Peroxide (The McCullough Protocol Method)

Sept 2026

If you want to add the virus-neutralizing power of hydrogen peroxide to your routine (and avoid triggering a thyroid flare w/ iodine-based gargles)  use a standalone, properly diluted peroxide throat rinse separately from your saline nasal rinses.

The Proper Gargle Dilution: Standard brown-bottle hydrogen peroxide from the pharmacy is a 3% concentration. This is too strong for the throat and can cause tissue burns. Dr. McCullough’s protocol instructs diluting it to a 1% solution.

The Recipe:

Mix 1 part 3% hydrogen peroxide with 2 parts clean water (for example: 1 tablespoon of hydrogen peroxide to 2 tablespoons of water).

The Application: Take 2 tablespoons of this diluted 1% solution, tilt your head back, and gargle for 30 seconds, then spit it out completely. Follow with a quick rinse of plain water to remove any lingering taste.

Your Best Sequence for Daily PreventionTo maximize your defense while maintaining your excellent health status, use a two-step approach:

Step 1 (Nasal): Use your homemade buffered saline and baking soda solution (or your commercial Xlear Natural Saline Nasal Spray) to rinse and clear your nasal passages.

Step 2 (Throat): Use the separately mixed, diluted 1% hydrogen peroxide solution to gargle and sanitize the throat.

Standard Homemade Nasal Saline Formula

Sept 21, 2026

Medical organizations like the [American Academy of Allergy, Asthma & Immunology (AAAAI)](https://www.aaaai.org/tools-for-the-public/conditions-library/allergies/saline-sinus-rinse-recipe) recommend the following balanced formula for sinus rinses:

* 3 teaspoons of non-iodized salt (such as canning, pickling, or kosher salt)
* 1 teaspoon of baking soda (pure sodium bicarbonate) [2, 3, 4]

Instructions:

   1. Thoroughly mix the dry salt and baking soda together and store the mixture in a small, clean, airtight container.
   2. When ready to use, measure 1 teaspoon of this dry mixture and dissolve it completely into 8 ounces (1 cup) of lukewarm water.
   3. Pour the liquid into a clean nasal spray bottle, bulb syringe, or neti pot for use.

Critical Safety Rules for Homemade Formulas
If you choose to make a nasal spray at home, you must adhere strictly to these safety protocols to prevent introducing dangerous pathogens directly into your sinuses:

* ⚠️ Never Use Plain Tap Water: Raw tap water contains low levels of amoebas and bacteria that are perfectly safe for your stomach to digest, but can cause fatal brain or sinus infections if introduced into the nasal passages. Only use distilled water, sterile water, or tap water that has been boiled vigorously for 3 to 5 minutes and cooled to lukewarm.

* Use Non-Iodized Salt Only: Iodized table salt contains chemical additives and anti-caking agents that can severely sting, burn, or inflame the delicate mucous membranes inside your nose.

* Do Not Skip the Baking Soda: Pure saltwater is acidic and will burn your nose. The baking soda acts as a buffering agent to balance the pH, matching your body’s natural chemistry and preventing irritation.

* Discard Regularly: Because homemade solutions lack chemical preservatives, any mixed liquid should be discarded and remade fresh after 24 to 48 hours to prevent bacterial growth.

McCullough Protocal Preventing & Managing Viral URIs

Sept 21, 2026

The current McCullough protocol for preventing and managing viral upper respiratory infections focuses heavily on an oral-nasal hygiene regimen intended to neutralize viruses at their entry points. Promoted by Dr. Peter McCullough through platforms like The Wellness Company, the core elements include: [1]

* Virucidal Nasal Sprays/Flushes: Done twice daily for routine prevention, or up to every 4 hours if actively exposed or symptomatic. This typically utilizes a diluted 1% povidone-iodine (PVP-I) solution (or alternatives like Xlear xylitol/grapefruit seed extract sprays, or diluted hydrogen peroxide if iodine-allergic).

* Oral Gargles: Gargling with a similarly diluted 1% povidone-iodine solution or standard antiseptic mouthwashes for 30 seconds twice daily to reduce viral loads in the throat.

* Nutritional Supplements: Daily preventive use of Zinc (50 mg), Vitamin D3 (5,000 IU), Vitamin C, and Quercetin (500 mg) to support general immune defense. [2, 3, 4, 5]

(Note: For post-infection recovery or addressing lingering viral proteins, he advocates for a separate oral regimen known as the Base Spike Detoxification (BSD) protocol, which consists of Nattokinase, Bromelain, and Curcumin). [6]

⚠️ Crucial Health & Safety Considerations
While topical antiseptics like povidone-iodine have demonstrated the ability to kill viruses in laboratory (in vitro) settings, their practical effectiveness in preventing or treating systemic viral infections in humans remains a subject of ongoing clinical debate and lacks definitive scientific consensus. [7, 8]
If you are considering adopting this regimen, please keep the following safety warnings in mind:

* Thyroid Risks: Povidone-iodine is highly absorbable through the mucous membranes. Regular or prolonged usage can alter thyroid function and elevate Thyroid-Stimulating Hormone (TSH) levels. It should never be used by individuals with thyroid disease, pregnant or nursing women, or anyone with an iodine allergy. [3, 4]

* Do Not Ingest: Iodine rinses and hydrogen peroxide must be diluted correctly according to proper medical guidance and never swallowed, as ingestion can cause gastrointestinal toxicity. [4]

* Standard Medical Prevention: Mainstream medical organizations—including the [CDC](https://www.cdc.gov/cfa-qualitative-assessments/php/data-research/season-outlook25-26-dec-update.html) and major health networks—maintain that the primary, evidence-based methods for avoiding severe respiratory viruses include seasonal vaccinations (for Flu, COVID-19, and RSV), frequent handwashing, staying home when sick, and using air filtration or ventilation. [9, 10, 11, 12, 13]

Always consult with your primary healthcare professional before introducing any new supplement protocol or nasal/oral chemical rinses to ensure they are safe for your personal health history.

[1] [https://www.linkedin.com](https://www.linkedin.com/posts/michelleshadwickmoeller_great-simple-health-tip-from-peter-mccullough-activity-7299880978963988480-5g3U)
[2] [https://www.victorymed.com](https://www.victorymed.com/covid-19-precautions/)
[3] [https://www.scribd.com](https://www.scribd.com/document/857506492/easy-and-effective-shield-from-covid-19-pdf)
[4] [https://medhelpclinics.com](https://medhelpclinics.com/resources/advice-from-the-doctor/at-home-treatment-protocol-for-covid-19)
[5] [https://www.linkedin.com](https://www.linkedin.com/posts/michelleshadwickmoeller_great-simple-health-tip-from-peter-mccullough-activity-7299880978963988480-5g3U)
[6] [https://pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC10663976/)
[7] [https://www.imrpress.com](https://www.imrpress.com/journal/RCM/22/2/10.31083/j.rcm2202033)
[8] [https://www.medrxiv.org](https://www.medrxiv.org/content/10.1101/2022.08.18.22278340v1.full-text)
[9] [https://www.cdc.gov](https://www.cdc.gov/cfa-qualitative-assessments/php/data-research/season-outlook25-26-dec-update.html)
[10] [https://share.upmc.com](https://share.upmc.com/2025/10/respiratory-virus-season/)
[11] [https://www.ama-assn.org](https://www.ama-assn.org/public-health/prevention-wellness/doctors-united-respiratory-virus-vaccine-recommendations)
[12] [https://www.sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S0002934320306732)
[13] [https://health.ri.gov](https://health.ri.gov/press-releases/ridoh-issues-vaccination-recommendations-respiratory-virus-season)

McCullough Spike Detox

Sept 2026

The current McCullough Protocol for addressing persistent spike proteins (from viral infections or vaccination) is known as the [Base Spike Detoxification (BSD) protocol] (https://pmc.ncbi.nlm.nih.gov/articles/PMC10663976/#:~:text=The%20protocol%20includes%20a,mechanisms%20of%20action%3A). [1, 2]

## Base Spike Detoxification (BSD) Regimen
The core oral triple-agent regimen proposed by Dr. Peter McCullough and colleagues consists of: [1, 3]

* Nattokinase: 2,000 FU (approx. 100 mg) orally twice daily on an empty stomach. (Aims to degrade spike protein and reduce clotting risks).

* Bromelain: 500 mg orally once daily on an empty stomach. (Aims to help break down proteins and support fibrinolysis).

* Curcumin: 500 mg orally twice daily. Nano, liposomal, or piperine-enhanced formulations are preferred for better absorption to help lower tissue inflammation. [3, 4, 5]

Key Mechanisms

* Proteolytic Cleavage: Nattokinase and bromelain target the breakdown of the spike protein structure.

* Anti-inflammatory: Curcumin helps suppress inflammatory pathways (such as NF-kB) triggered by spike fragments.

* Vascular Support: Helps with the dissolution of microthrombi and provides anticoagulant support. [1, 5]

Note: Medical mainstream organizations note that large-scale, randomized controlled trials for spike detoxification protocols remain limited, and patients taking concurrent blood thinners or antiplatelet drugs must exercise caution with nattokinase. [4, 6]

[1] [https://pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC10663976/)
[2] [https://www.researchgate.net](https://www.researchgate.net/figure/McCullough-Protocol-Base-Spike-Detoxification-BSD-A-Dissolution-of-spike_fig2_375814234)
[3] [https://www.ifmsynergy.com](https://www.ifmsynergy.com/the-mccullough-protocol-for-long-covid-what-the-evidence-actually-shows/)
[4] [https://www.biospace.com](https://www.biospace.com/potential-covid-spike-protein-detoxification-regime-discussed-in-journal-of-american-physicians-and-surgeons-aaps)
[5] [https://www.researchgate.net](https://www.researchgate.net/figure/McCullough-Protocol-Base-Spike-Detoxification-BSD-A-Dissolution-of-spike_fig2_383114457)
[6] [https://pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/38024037/)

Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID-19 Protection for Health Care Worker (HCW), for all

Published online 4/8/2022

Published PubMed Oct 2022

Benefits of PVP-I Oro-Nasal Spray in Brief

Benefits of 0.6% PVP-I

  • Effective virucidal agent against all coronaviruses, including SARS- COV-2.
  • Effective in case of both pre and post exposure.
  • Effective for healthy individual (for protection) as well as COVID-19 patient also ( for reduction of viral load and SARS-CoV-2 transmissibility for close contacts/ family members).
  • Almost no side effect (mucosal irritation, thyroid dysfunction, teeth staining,).
  • This minimum concentration of PVP-I (0.6%) has least possibility of doing any harm to human body (nasal or oral mucosa). More concentration is being used on eye, ear, mucosa of oral cavity, oropharynx since before.
  • No chance of resistance
  • Reduces disease burden by minimizing sign- symptoms, like-nasal congestion, sore throat.

Benefits of Oro-Nasal Spray

  • Single container, double function (PVP-I Oral/Throat spray as well as Nasal spray)
  • Easy to carry (in pocket, handbag)
  • Easy to use
  • No need to have a basin or a facility to gargle or spit
  • Minimum amount of PVP-I solution is needed (20 ml solution can be used for 20- 30 days for regular user.)
  • Cheap (to refill)
  • Minimum Iodine exposure.
  • Container can be reusable and refillable.

Recommendations

PVP-I Oro Nasal Spray should be used by doctors or other health care workers (HCW), COVID-19 patients as well as common people.

For Doctors or Other Health Care Workers (HCW).

  • Prior to visit any patient in any facility irrespective of COVID status
  • Prior to examining the oral cavity, throat or nose of any patient
  • Prior to any Surgery, specially surgery of Nose, mouth, throat, ear, skull base
  • Prior to attend COVID-19 patient in a COVID-19 dedicated unit / hospital
  • Following exposure to confirmed or suspected COVID patient (intentional/accidental)

For Common People

  • Prior to attend public gathering or working outside home, where there is chance of known or unknown COVID-19 patient/ SARS-CoV-2 exposure.
  • Before leaving and after returning home and in between 1 or 2 time (after tea/lunch/dinner break).
  • For COVID-19 patientsAs it has the potentiality to reduce the viral load, it will definitely reduce the viral transmission from patient to healthy person. Again, it may have positive role on treatment, in mortality and morbidity index. To prove this further studies are recommended.
  • How to use: 2–3 puff in each nostril and 1–3 puff in throat (oral cavity and oropharynx) in 3–4 h interval.
  • How long? Though it is proved and established that long term (1–2 months) application of this minimum amount of PVP-I is quite safe SPS:refid::bib2|bib3|bib4[2,3,4]. But, I recommend after continuous use of 1–2 week 1 day interval (weekly holiday) should be given.

Conclusion

PPE, mask, hand sanitization or vaccines nothing proved 100% effective for COVID-19 prevention still now. PVP-I oro-nasal spray is an easy tool or way for COVID-19 prevention and reduction of SARS-CoV-2 transmissibility. I recommend here, this oro-nasal spray should be used as an adjunct to PPE, mask or vaccine. Any person, policy maker, local or central government could adopt this safe, cheap, easily available and effective PVP-I Oro-Nasal spray as an additional shield of their COVID-19 protection and thus minimize the COVID burden.

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8026810/

McCullough Protocol©: Nasal-Oral Viricidal Washes and Gargles

UPDATE 9/1/2026
Research, which was presented at the ESC Cardiology Congress in Germany this week, showed that higher levels of xylitol in the blood were associated with an increased risk of major adverse cardiovascular events.

*******

Oct 2022

Everyone is familiar with nasal and oral swab testing for COVID-19.  It should be obvious the virus is replicating in the nose, and with Omicron, the speed of replication has become much greater than the prior strains of the virus.  Thus, there is a wonderful opportunity to reduce viral replication, in fact, kill viruses with agents directly applied in the nasal cavity and the back of the throat.  

Use of directly applied therapy is far more effective than swallowing pills or capsules or receiving an intravenous infusion.  The nasal mucosa is a barrier for entry and if functioning well, allows little penetration of virions into systemic circulation where for example a monoclonal antibody could work.  Thus, the McCullough Protocol© starting in 2021, featured the upfront use of nasal washes and oral gargles using viricidal agents.[ii]  

Many have asked which solutions, mixtures, and frequencies should be used?   One should be reassured that is far more important to use some form of nasal and oral topical therapy as opposed to letting the infection take its course and ultimately invade the lungs and the internal organs. 

For purposes of this stack, we acknowledge that many can be effective including:  povidone-iodine, hydrogen peroxide, colloidal silver, xylitol, and for the throat many mouthwashes including Scope and Listerine. 

Principles are 1) nasal solutions should be comfortable and not sting with sufficient dilution, 2) sniffed far back into the sinuses and then spit out through the mouth (often causes coughing or mild choking), done at least twice per nostril per session, 3) oral gargles should be for 30 seconds and then spit out. 

For detailed descriptions of products and solutions please visit one of several websites to get this practical information.[iii] 

Oropharyngeal viricidal therapy has been demonstrated in supportive studies and randomized trials to:  1) prevent infection after suspected exposure (twice daily), 2) reduce the period of infectivity when ill, and 3) attenuate the progression of disease and reduce the need for oxygenation and hospitalization (six times daily). 

https://petermcculloughmd.substack.com/p/mccullough-protocol-nasal-oral-viricidal?utm_source=substack&utm_campaign=post_embed&utm_medium=email

Mouth Washes That Inactivate Coronaviruses

Oct 21, 2020 (note the date)

Description

Mouth Washes That Inactivate Coronaviruses

Please read and agree to the disclaimer before watching this video.

Mouth Washes That Inactivate Coronaviruses: Study finds the SARS-COV-2 is inactivated by some of the oral rinsing products https://academic.oup.com/jid/article/…

Study finds that some mouth washes and nasal rinses help reduce virus load by greater than 90% https://onlinelibrary.wiley.com/doi/1…

An article for the above study https://www.yahoo.com/lifestyle/mouth…

How to perform a nasal rinse •video

A study in Malaysia finds rapid virus clearing in SARS-COV-2 patients https://clinicaltrials.gov/ct2/show/s…

Polyvidone https://en.wikipedia.org/wiki/Polyvin… #drbeen #koolbeens #COVID-19 …

Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. … Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.