Author: Sharon

https://www.cidrap.umn.edu/news-perspective/2020/05/autopsies-covid-19-patients-reveal-clotting-concerns

Notice the Von Willebrand factors in the image? Take a quick read at the above link and see what they’re finding.

(Also see Dr. Caldwell Esselstyn’s BRIEF description of endothelial function HERE. )

https://vimeo.com/408592657

MAY 8, 2020

https://www.thenewamerican.com/usnews/health-care/item/35678-expert-testimony-before-senate-contradicts-medias-covid-19-narrative

“Called theFront Line COVID-19 Critical Care (FLCCC) Working Group, the physicians involved call their treatment for the disease the MATH+ protocol. It was developed specifically to counteract the inflammation and excess clotting that is experienced by severe COVID-19 sufferers.”

There it is again – symptoms of a disease of the endothelium.

April 21, 2020: Personal precautions one pulmonologist (who is treating SARS-CoV-2 patients daily) takes in his own personal life.

IMMPORTANT: CONSULT FIRST WITH YOUR OWN PHYSICIAN
Doctor’s Personal Regimen

* Vit C 500 mg/twice daily

* Vit D 2,500 IU/day (same as 62.5 mcg/day)

* Quercetin 500 mg/twice daily (found in onions, capers, etc)

* n-acetyl cysteine (NAC) 600 mg/twice daily

* Zinc rda=40 mg/day, don’t overdose b/c reduces copper absorption (when exposed to covid he increases to 50, but only for short time)

* Sleep 7-8 hrs/night

IN YOUR CAR:
* Hand Sanitizer
* Garbage Bag
* Disinfectant Wipes
* Surgical Mask

Member of UK’s Scientific Advisory Group for Emergencies has stepped down after breaking his own social distancing recommendations. Epidemiologist Neil Ferguson reports that he thought himself medically immune when he broke quarantine. [I’m only mentioning this article because Ferguson’s paper was instrumental in so many countries locking down. This action is destroying economies out of an abundance of caution, so people are troubled that he is not more careful following his own recommendations.]

https://www.cnn.com/2020/05/05/uk/neil-ferguson-imperial-coronavirus-sage-gbr-intl/index.html

It is suggested that results may be different if administered early and/or in combination with zinc. Studies continue.

Before we begin please note the October 2015 peer-reviewed research paper reporting that early treatment with hyroxychloroquine prevents the development of endothelial dysfunction in Lupus.

And now on to SARS-COV-2 Endothelial Function – Part 4:

First we review:

• SARS-COV-2 attacks the ACE 2 receptor
• Results in increase of AT-II & reduction of AT 1,7
• This causes increase in super oxide creation (oxidative stress)
• Which causes endothelial cell dysfunction through nitric oxide pathway
• VWF (Von Willebrand factor) gets spilled out
• Causing an increase in thrombosis (blood clot) at the location of the inflammation

In this new video lesson we learn of a May 2004 research paper describing how African Americans have a lower cellular bioavailability of nitric oxide (NO), which limits their reduction of oxidative stress. (Remember oxidative stress is not desirable, it damages the endothelial.)

This could explain, among other factors, why particular ethnic groups are experiencing increased severity in coronavirus infections.

Covid-19 disease appears to induce an illness in young children similar to Kawasaki (vascular) disease.

A paper published in 2010 is discussed in the video. Researchers hypothesize that in typical Kawasaki disease a pathogen, probably a virus, invades via the respiratory and digestive organs. (This is precisely what doctors are seeing with coronavirus disease.) Also cytoplasmic inclusion bodies were observed in bronchial endothelium.

Perhaps Kawasaki disease is a response to the body’s inflammation and immune system in response to fighting a virus. This may explain why we are seeing more Kawasaki-type disease at the same time coronavirus is circulating in the population.

(See Dr. Caldwell Esselstyn’s BRIEF description of endothelial function HERE. )