Member of UK’s Scientific Advisory Group for Emergencies has stepped down after breaking his own social distancing recommendations. Epidemiologist Neil Ferguson reports that he thought himself medically immune when he broke quarantine. [I’m only mentioning this article because Ferguson’s paper was instrumental in so many countries locking down. This action is destroying economies out of an abundance of caution, so people are troubled that he is not more careful following his own recommendations.]
During this interview Swedish epidemiologist Johan Giesecke questions the choice made by so many countries to enact severe covid lock-downs & comments on how a single unpublished, non peer-reviewed paper (by epidemiologist Neil Ferguson of London’s Imperial College) was foundational to this action.
And now on to SARS-COV-2 Endothelial Function – Part 4:
First we review:
SARS-COV-2 attacks the ACE 2 receptor
Results in increase of AT-II & reduction of AT 1,7
This causes increase in super oxide creation (oxidative stress)
Which causes endothelial cell dysfunction through nitric oxide pathway
VWF (Von Willebrand factor) gets spilled out
Causing an increase in thrombosis (blood clot) at the location of the inflammation
In this new video lesson we learn of a May 2004 research paper describing how African Americans have a lower cellular bioavailability of nitric oxide (NO), which limits their reduction of oxidative stress. (Remember oxidative stress is not desirable, it damages the endothelial.)
This could explain, among other factors, why particular ethnic groups are experiencing increased severity in coronavirus infections.
Covid-19 disease appears to induce an illness in young children similar to Kawasaki (vascular) disease.
A paper published in 2010 is discussed in the video. Researchers hypothesize that in typical Kawasaki disease a pathogen, probably a virus, invades via the respiratory and digestive organs. (This is precisely what doctors are seeing with coronavirus disease.) Also cytoplasmic inclusion bodies were observed in bronchial endothelium.
Perhaps Kawasaki disease is a response to the body’s inflammation and immune system in response to fighting a virus. This may explain why we are seeing more Kawasaki-type disease at the same time coronavirus is circulating in the population.
(See Dr. Caldwell Esselstyn’s BRIEF description of endothelial function HERE. )
It appears Youtube has now deleted this video. It’s very frustrating to try to gather information from professional people (in this case a well-respected epidemiologist and a doctor of medicine) when YouTube decides we shouldn’t hear it.
I will try to find this interview elsewhere and post it here, if I find it.
Okay, I found a copy. Better listen soon, this one will inevitably be banned by YouTube:
********
Time is warping during this lockdown, weeks feel like years…
I’ve been following Kurt Wittkowski for over a month and his opinion has not deviated. He just sits there calmly and waits for the facts to unfold with time.
