March 18, 2024
https://www.nature.com/articles/s41380-024-02509-5
Given the challenges of developing effective pharmacological treatments for Alzheimer’s Disease and other brain diseases, alternative strategies including low-intensity focused ultrasound (FUS) are currently being explored. At high intensity, ultrasound is being used as a focused, incisionless, FDA-approved surgical tool for ablating brain tissue and thereby treating diseases such as essential tremor and tremor-dominant Parkinson’s disease. At low intensity, ultrasound is being investigated as neuromodulatory and/or blood-brain barrier (BBB) opening tool in multiple animal species and human study participants.